The excitment about Dutasteride is the fact that it has proven to be more effective and faster acting than any other treatment thus far in the fight aqainst hair loss. Dutasteride works by blocking the formation of DHT 5 alpha-dihydrotestosterone. What makes Dutasteride even more effective is it’s ability to also inhibit both types of 5-alpha reductase (5AR).As with other hair loss drugs women should not take Dutasteride. In fact pregnant women should not even handle the drug as it is easily absorbed through the skin. Dutasteride can cause serious side effects in newborns. Birth defects may occur when large amounts of the drug are absorbed into the body during the period of fetal development. Men who have taken Dutasteride should not donate blood for atleast 6 months after stopping treatment.Propecia and Avodart should be taken once a day. It has been found that after two years of treatment, Propecia effectively grows hair in about 66% of patients. Also, about 83% of the subjects receiving this treatment continue to maintain their existing hair after two years [avodart online].Dutasteride, there are other treatment options (all topical) that may or may not work to block the effects of DHT on vulnerable hair follicles. These include Revivogen, Crinagen, Progesterone Creams, and Xandrox (a type of minoxidil).Today it is detrimental to solve these problems now while there is still time to act on it. With the topic of hair loss, there are many ways to treat this particular ailment, and if this is a problem you are suffering from there is hope. The essence of this article is to make you a more aware consumer before you spend money on any particular hair loss treatment [avodart online].Sometimes with all the advertisements out there, you can become easily confused or frustrated over the state of your own hair loss, and it can take time to remove the commercial blinders so common to our society today. There is a way to get through all the hype, and find that which will treat your condition the best means possible, and with the most sufficient results to prevent any further hair loss. With all the viable procedures created and administered by professional physicians.With issue of your hair loss, some definite research and forethought needs to go into your idea of treatment, and always consult your doctor a bit before using or participating in any one of the particular procedures listed.

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Some of the more popular treatments are the chemical treatments like: Propecia, Rogaine, Avodart, and Nizoral. Other alternatives to these particular products are surgical hair replacement, or transplanting as it is sometimes called, and alternate non-surgical methods.It can be rather time-consuming wading through these many treatments to find the answer, but with the advice and information listed here, you may just be the most acute shopper that you can be with matters of this kind [avodart online]. A doctor prescribes all of the chemical procedures, and the FDA has approved these two for use, Rogaine and Propecia. Rogaine is a topical lotion that stimulates hair growth, and Propecia is an oral pill taken to block an enzyme linked with pattern baldness in males.After six month of treatment, the hair counts measured in a 1 inch diameter circle increased by about ~96 hairs with 0.5mg Dutasteride, compared to about ~72 hairs with 5mg Finasteride. The hair counts increased significantly with an increase in dosage with the biggest gain being ~108 hairs with a dose of 2.5mg Dutasteride. So compared to 5mg Finasteride (Proscar), 2.5 mg Dutasteride grew about 1.5 times as many hairs. This is why there is so much excitement surround Dutasteride online. However, there are still unknown questions about increased side effects compared to Finasteride. The Phase III study should tell much more.

In 2002, the FDA approved Avodart (dutasteride 0.5mg) for the treatment of prostate enlargement in men (the medical term is symptomatic benign prostatic hyperplasia or BPH). Dutasteride is not approved for the treatment of male pattern hair loss.
Like finasteride (the active ingredient in Propecia), avodart is an inhibitor of the enzyme 5 alpha-reductase responsible for the conversion of testosterone to DHT (dihydrotestosterone). However, unlike finasteride, which only inhibits the Type I form of the enzyme, dutasteride inhibits both the Type I and Type II forms of the 5 alpha-reductase enzyme. This dual effect makes the drug more potent but also increases the incidence of adverse reactions.The Type II form of the enzyme is found predominantly in the hair follicle [buy avodart]. The Type I form of the enzyme has been found in the scalp and sebaceous glands, but its exact role in hair growth has not been determined.

Effects on Hair Growth

Dutasteride 0.5mg/day decreases serum DHT 91% and scalp DHT 54%. Finasteride 5mg/day decreases serum DHT 71% and scalp DHT 38%. Based on these results, dutasteride should be significantly more effective in the treatment of androgenetic alopecia than finasteride. However, since the Type I form of the 5 alpha-reductase that dutasteride blocks is not present in significant quantities in the hair follicle, these effects may not be as significant as one might expect [buy avodart]. The increased efficacy of Avodart is felt to be due, in part, to its effects on lowering serum DHT.
A study by Olsen et al. published in the Journal of the American Academy of Dermatology in 2006 has showed the benefits of dutasteride over finasteride in a scientifically rigorous, placebo-controlled study.

Side Effects Of Avodart

Dutasteride was investigated in controlled multi-center studies involving 4,325 men aged 50 and above with prostate enlargement. Drug-related side effects during the first six months were as follows: impotence (4.7 percent vs. 1.7 percent for placebo), decreased libido (3 percent vs. 1.4 percent), breast tenderness and breast enlargement (gynecomastia; 0.5 percent vs. 0.2 percent) and ejaculation disorders (1.4 percent vs. 0.5 percent).The incidence of most drug-related sexual adverse events decreased with duration of treatment. The incidence of drug-related breast tenderness and breast enlargement remained constant over the treatment period [buy avodart]. Ejaculate volume may be decreased in some patients with continued treatment. This decrease did not appear to interfere with normal sexual function.

Effects on PSA

Avodart will reduce the amount of PSA measured in the blood and this must be taken into account when PSA is used in the detection of prostate cancer. Even though both finasteride and dutasteride were developed to combat benign prostatic hyperplasia by reducing DHT in prostate tissue, some scientists question the wisdom of using these 5-alpha reductase inhibitors in younger men who have no problem with their prostates. A research chemist [buy avodart], Patrick Arnold, says “Evidence is mounting that the existence of a high estrogen/androgen ratio – a condition common in older men – is highly correlated with the development of benign prostatic hyperplasia.”[citation needed] However, in apparent contradiction, individuals with 5-alpha-reductase deficiency (and thus a similar hormonal profile to users of DHT inhibitors) do not experience BPH.
Avodart does work for hair loss. Dihydrotestosterone is the main molecule responsible for androgenic alopecia or hair loss. Finasteride, which reduces transformation of testosterone into dihydrotestosterone (DHT) and decreases dihydrotestosterone activity, is approved for treatment of androgenic hair loss in men. In one case study, a 46-year-old woman with androgenic alopecia, non-responsive to minoxidil, who initially benefited from finasteride, was given another 5-reductase inhibitor, Avodart. Clinical evaluation and trichogram were applied for assessment of Avodart efficacy in this patient. Additionally, mean hair diameter was monitored by means of computer dermoscopy. After 6 months of therapy, significant improvement was observed and after 9 months the clinical diagnosis of androgenic alopecia could no longer be made in this patient. Avodard is helpful for hair loss. Avodart dosage for hair loss may be less that the dosage required to treat prostate enlargement. For more information on baldness [buy avodart].I read with interest your articles on the potential side effects of Avodart and found it disturbing that some of the Avodart side effects such as musculoskeletal pain were not mentioned on the official Avodart website. On another web site, almost 10% of posters related anecdotes about experiencing unusual pain after taking Avodart. My father is an otherwise healthy 84 y/o Caucasian male. He began taking Avodart for BPH approximately 18 months ago. About 4 months ago he began complaining of joint pain and stiffness, especially in his shoulders and knees, which was more severe at night and upon awakening. He also developed a shortened gait and had some difficulty in walking normally [buy avodart]. He frequently required morning pain relief, which he obtained by taking naproxen or Tylenol, one to two tablets per day. He visited his primary care physician who made an initial diagnosis of arthritis, however, later x-ray imaging of the shoulders showed no significant degeneration or other changes consistent with arthritis, and there is no family hx of arthritis. Approximately one month ago he received cortisone injections in both shoulders, which resulted in some significant pain relief lasting for about 10 days. Additional changes in his body habitus which I observed recently include some possible generalized muscle atrophy and an increased resting heart rate. Just 6 months ago he was much more vigorous and more agile than many 60 year olds. About one week ago (August 06) he consulted with his urologist and was instructed to discontinue taking Avodart for 30 days, although the urologist was unaware that musculoskeletal pain is a potential Avodart side effect. Since that time my father has reported some slight improvement, with reduced joint pain, and he has required less frequent oral pain medication. He takes no other prescription medications except Timoptic (ophthalmic) for glaucoma and is otherwise healthy [buy avodart]. He has never had his testosterone levels checked. I am concerned that if his testosterone levels are low and given that conversion to the more androgenic DHT form is blocked by the Avodart, he may be at increased risk for osteoporosis and other side effects of low testosterone levels. Can you provide any recommendations on how to proceed in evaluating and treating him, which he could then discuss with his primary care physician and his urologist?

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